A novel and highly efficient esterification process using triphenylphosphine oxide with oxalyl chloride

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A novel and highly efficient esterification process using triphenylphosphine oxide with oxalyl chloride

Triphenylphosphine oxide (TPPO) and oxalyl chloride ((COCl)2) are used as novel and high-efficiency coupling reagents for the esterification of alcohols with carboxylic acids via the TPPO/(COCl)2 system at room temperature for 1 h. The reaction represents the first TPPO-promoted esterification under mild and neutral conditions with excellent yields. Furthermore, we proposed a plausible mechanis...

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Utility of Triphenylphosphine Dihalides in Organic Reactions : Esterification Using Triphenylphosphine Dibromide as the Dehydrating Agent

A new esterification method was investigated using triphenylphosphz'ne dibromide as a dehydrating agent. This investigation has established that the method is useful when the acid is aromati~ or arylallylic. That primary and secondary alcohols esteTZfy acid satisfactorily whereas tertiary alcohols fail to react was also established in this experiment.

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A novel tetrakis(pyrazolyl)borate ligand bearing triphenylphosphine oxide substituents.

A new tetrakis(pyrazolyl)borate ligand bearing triphenylphosphine oxide moieties appended to the 3-position of the pyrazolyl rings is reported and shown to display varied coordination chemistry from tridentate N(2)O coordination with thallium to hexadentate N(3)O(3) coordination with europium.

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Removal of Triphenylphosphine Oxide by Precipitation with Zinc Chloride in Polar Solvents

While the use of triphenylphosphine as a reductant is common in organic synthesis, the resulting triphenylphosphine oxide (TPPO) waste can be difficult to separate from the reaction product. While a number of strategies to precipitate TPPO are available, none have been reported to work in more polar solvents. We report here that mixing ZnCl2 with TPPO precipitates a TPPO-Zn complex in high yiel...

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Complexes of triphenylphosphine oxide with lanthanide bromides

The reaction between hydrated lanthanide bromides and triphenylphosphine oxide in 1:3 and 1:4 ratios in ethanol gave a series of complexes [LnBr2(Ph3PO)4]Br (Ln = Pr, Nd, Gd, Tb, Er, Yb, Lu) which contain ethanol and water in the lattice, regardless of the ratio of reactants used. The single crystal x-ray structures of [NdBr2(Ph3PO)4]Br, [GdBr2(Ph3PO)4]Br and [YbBr2(Ph3PO)4]Br have been determi...

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ژورنال

عنوان ژورنال: Royal Society Open Science

سال: 2018

ISSN: 2054-5703

DOI: 10.1098/rsos.171988